Category: Systematic review with network meta-analysis
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SPOR Evidence Alliance
Summary The Strategy for Patient-Oriented Research (SPOR) Evidence Alliance is a partnership between researchers, patients and members of the public, healthcare providers, health system managers, policy-makers, and other decision-makers across Canada (and beyond) who are committed to building a Canadian health system that is increasingly informed and improved using the best available health research evidence.…
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Sustaining knowledge translation interventions for chronic disease management in older adults: A systematic review and network meta-analysis
Summary This is a systematic review and network meta analysis of effectiveness and cost-effectiveness of sustainability of knowledge translation (KT) interventions that target chronic disease management (CDM) for end-users, including older patients, beyond 1 year after implementation. This also entailed an economic analysis of the interventions identified to be effective. Project Resources Funded By Principal…
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Development of a risk of bias tool
Summary The objective of this project was to conduct (a) a Delphi process to determine expert opinion on an item’s inclusion and (b) a knowledge user survey to widen its impact. Most knowledge users and Delphi panelists preferred a tool to assess both bias in individual network meta-analysis (NMA) results and authors’ conclusions. This Delphi…
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PRISMA extensions for rapid reviews, scoping reviews, and network meta-analysis
Summary The PRISMA extensions for NMA and ScR were published in 2015 and 2018. Since then, their methodologies and innovations, including automation, have evolved. There is no reporting guideline for RRs. In 2020, an updated PRISMA statement was published reflecting advances in the conduct and reporting of systematic reviews. These advances are not yet incorporated…
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Comparing effectiveness of sustainability of knowledge translation interventions for chronic disease management in older adults
Summary This is a systematic review and network meta analysis of effectiveness and cost-effectiveness of sustainability of knowledge translation (KT) interventions that target chronic disease management (CDM) for end-users, including older patients, beyond 1 year after implementation. This also entailed an economic analysis of the interventions identified to be effective. Project Resources Funded By Principal…
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Efficacy of the trivalent and quadrivalent influenza vaccines relative to one another among adults 60 years of age and older: A systematic review and network meta-analysis
Summary This network meta-analysis aimed to compare the efficacy of influenza vaccines of any valency for adults 60 years and older. It demonstrated efficacy associated with IIV3-HD and RIV vaccines in protecting older persons against LCI, and RIV vaccine may reduce all-cause mortality when compared with other vaccines, but the evidence is uncertain. However, differences…