Anti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis
Pham B, Thomas SM, Lillie E, Lee T, Hamid J, Richter T, Janoudi G, Agarwal A, Sharpe JP, Scott A, Warren R, Brahmbhatt R, Macdonald E, Straus SE, Tricco AC. Anti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis. BMJ Open. 2019 May 28;9(5):e022031. doi: 10.1136/bmjopen-2018-022031.
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Commissioned and Funded by: Canadian Institutes of Health Research (CIHR) through the Drug Safety and Effectiveness Network (DSEN)
- Our results can be used by patients and their healthcare providers, as well as policy-makers to guide decision-making regarding use of the anti-VEGF agents
- Anti-VEGF agents are effective for improving vision gain, mean BCVA, and reducing vision loss for patients with wet AMD
- Compared to placebo, we did not observe an association between their use and increased adverse events or mortality
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Date : 11 Aug 2020