Research briefs are a one page summary of our reviews and knowledge synthesis projects published alongside our reports to provide knowledge users with a high-level overview of our methods and main findings.
Systematic Review Process Map
This tool was developed by the St. Michael’s hospital KT program. We have a defined and rigorous process for all our systematic reviews. This process map tool takes you through the steps to conduct a systematic review.
- The Cochrane Collaboration
- The Cochrane Library
- Canadian Cochrane Network and Centre
- The Campbell Collaboration
- The Joanna Briggs Institute
- AHRQ Evidence Based Practice Center Program
- Centre for Reviews and Dissemination
- CIHR A Guide to Knowledge Synthesis
- Centre for Evidence-based Medicine
- EPPI Centre
- KT Canada
- PROSPERO: International Prospective Register of Systematic Reviews
- Enhancing the QUAlity and Transparency of health Research, EQUATOR Network
- Canadian Agency for Drugs and Technologies in Health, CADTH
- Medical Research Council Biostatistics Unit
- Multiple Treatments Meta-Analysis
- Multi- parameter Evidence Synthesis Research Group, University of Bristol
- Higgins, J. P., & Green, S. (Eds.). (2011). Cochrane Handbook for Systematic Reviews of Interventions (Version 5.1.0). The Cochrane Collaboration. Available from https://handbook-5-1.cochrane.org/.
- Akers, J., Aguiar-Ibáñez, R., & Baba-Akbari Sari, A. (2009). CRD’s guidance for undertaking reviews in health care. York, UK: Centre for Reviews and Dissemination (CRD).
- Straus, S., Tetroe, J., & Graham, I. D. (Eds.). (2013). Knowledge translation in health care: moving from evidence to practice. John Wiley & Sons.
- Antman, E. M., Lau, J., Kupelnick, B., Mosteller, F., & Chalmers, T. C. (1992). A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts: treatments for myocardial infarction. JAMA, 268(2), 240-248. doi:10.1001/jama.1992.03490020088036/.
- Eden, J., Levit, L., Berg, A., & Morton, S. (Eds.). (2011). Finding what works in health care: standards for systematic reviews. National Academies Press.
- Jansen, J. P., Trikalinos, T., Cappelleri, J. C., Daw, J., Andes, S., Eldessouki, R., & Salanti, G. (2014). Indirect treatment comparison/network meta-analysis study questionnaire to assess relevance and credibility to inform health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report. Value in Health, 17(2), 157-173. doi:10.1016/j.jval.2014.01.004.
- Methods Guide for Effectiveness and Comparative Effectiveness Reviews [Internet]. (2008). Rockville (MD): Agency for Healthcare Research and Quality (US). Available from http://www.ncbi.nlm.nih.gov/books/NBK47095/.
- Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of Internal Medicine, 151(4), 264-269. doi:10.7326/0003-4819-151-4-200908180-00135.
- Review Manager (RevMan): Version 5.3 [Computer program]. (2014). Copenhagen: The Nordic Cochrane Centre. Available from http://tech.cochrane.org/revman.
Knowledge Synthesis for Knowledge Users
Insulin for type 1 diabetes
A third of systematic reviews changed or did not specify the primary outcome: a PROSPERO register study
A scoping review identifies multiple emerging knowledge synthesis methods, but few studies operationalise the method
Knowledge synthesis methods for integrating qualitative and quantitative data: A scoping review reveals poor operationalisation of the methodological steps
Knowledge synthesis methods for generating or refining theory: A scoping review reveals that little guidance is available
Conceptual recommendations for selecting the most appropriate knowledge synthesis method to answer research questions related to complex evidence
News & Media
Anti-nausea Medication Used Post-operatively
- Certain anti-nausea medications used after operation could increase risk for irregular heartbeat -Health, medical and science updates – Published Online. (June 19, 2015). Video available from http://www.news-medical.net/news/20150619/Certain-anti-nausea-medications-used-after-operation-could-increase-risk-for-irregular-heartbeat.aspx.
- Some Common Anti-nausea Medications Used Post-operatively Could Increase Patients' Arrhythmia Risk - Science Newsline Medicine- – Published Online. (June 18, 2015). Video available from http://www.sciencenewsline.com/articles/2015061814330022.html.
- Bill Beckwith's Memory Minute: Do Cognitive Enhancers Benefit Those with Mild Cognitive Impairment? – Naples Daily News – Published Online. (October 8, 2013). Video available from http://www.naplesnews.com/lifestyle/neapolitan/bill-beckwiths-memory-minute-do-cognitive-those.
- Cognitive enhancers don't help after 96 weeks in mild cognitive impairment for Alzheimer's patients – Drug Topics – Published Online. (September 26, 2013). Video available from http://drugtopics.modernmedicine.com/drug-topics/news/cognitive-enhancers-don-t-help-after-96-weeks-mild-cognitive-impairment-alzheimer-s?page=full.
- Dementia Drugs No Help in Mild Impairment – MedPage Today – Published Online. (September 22, 2013). Video available from http://www.medpagetoday.com/Neurology/Dementia/41657
- Cognitive enhancers don't work for mild impairment – The Globe and Mail – Published Online. (September 17, 2013). Video available from http://www.theglobeandmail.com/life/health-and-fitness/health/cognitive-enhancers-dont-work-for-mild-impairment/article14373432/.
- Study shoots down AD drug class in mild patients – Medical Marketing and Media – Published Online. (September 17, 2013). Video available from http://www.mmm-online.com/study-shoots-down-ad-drug-class-in-mild-patients/article/312032/.
- Alzheimer's drugs lack benefit for mild cognitive impairment, researchers conclude – Global News – Published Online. (September 17, 2013). Video available from http://globalnews.ca/news/845405/alzheimers-drugs-lack-benefit-for-mild-cognitive-impairment-researchers-conclude/.
- Drug nixed for mild cognitive impairment: study - The Toronto Star- Published Online. (September 16, 2013). Video available from http://www.thestar.com/life/health_wellness/2013/09/16/drug_nixed_for_mild_cognitive_impairment_study.html.
- Alzheimer's drugs may harm people with mild memory issues: 'Cognitive enhancers' may cause GI problems in patients with mild cognitive impairment - CBC News – Published Online. (September 16, 2013). Video available from http://www.cbc.ca/m/touch/health/story/1.1855890.
- Study finds cognitive enhancers do not improve cognition or function in people with mild cognitive impairment but may cause gastrointestinal issues – HealthCanal.com – Published Online. (September 16, 2013). Video available from http://www.healthcanal.com/mental-health-behavior/42932-study-finds-cognitive-enhancers-do-not-improve-cognition-or-function-in-people-with-mild-cognitive-impairment-but-may-cause-gastrointestinal-issues.html.
Cost-effective Treatments for Complex Wounds
- Papers identify effective and cost-effective treatments for complex wounds – HealthCanal – Published Online. (April 23, 2015). Video available from http://www.healthcanal.com/public-health-safety/62687-papers-identify-effective-and-cost-effective-treatments-for-complex-wounds.html.
- Papers Identify Effective And Cost-effective Treatments for Complex Wounds – Science News Line – Published Online. (April 22, 2015). Video available from http://www.sciencenewsline.com/articles/2015042223470026.html.
- Meta-Analysis of Quality Improvement Strategies in Treating Diabetes, FRMC TV. (June 19, 2015). Video available from http://www.firstreportnow.com/frmctv/andrea-c-tricco-msc-phd-discusses-meta-analysis-quality-improvement-strategies-treating-dia
- Implementing new care strategies can cut health care usage among system’s biggest users – PharmacyChoice- Published Online. (September 29, 2014). Video available from http://www.pharmacychoice.com/News/article.cfm?Article_ID=1262167.
- New Care Strategies to Cut Health Care Usage Among System’s Biggest Users - Health Canal- Published Online. (September 15, 2014). Video available from http://www.medindia.net/news/new-care-strategies-to-cut-health-care-usage-among-systems-biggest-users-141336-1.htm.
- New research finds flu shot effective regardless of circulating strains - Vaccine News Daily – Published Online. (June 28, 2013). Video available from http://vaccinenewsdaily.com/vaccine_development/325801-new-research-finds-flu-shot-effective-regardless-of-circulating-strains/.
- How Civilization As We Know It Could End ... With A Cough - Forbes – Published Online. (June 27, 2013). Video available from http://www.forbes.com/sites/markgibbs/2013/06/27/how-civilization-as-we-know-it-could-end-with-a-cough/.
- Many programs to help diabetics manage their health do work - Diabetes news – Published Online. (June 22, 2012). Video available from http://www.health.am/db/more/many-programs-to-help-diabetics/.
Insulin Regiments for Diabetes
- Study compares insulin regiments for type 1 diabetes - NBC Right Now KNDU-TV- Published Online. (October 4, 2014). Video available from http://www.nbcrightnow.com/story/26696675/study-compares-insulin-regimens-for-type-1-diabetes.
- Study compares insulin regiments for type 1 diabetes - WGEM.com- Published Online. (October 4, 2014). Video available from http://www.wgem.com/story/26696675/study-compares-insulin-regimens-for-type-1-diabetes.
- Long-acting insulin is safer, more effective for patients with Type 1 diabetes – ScienceDaily- Published Online. (October 3, 2014). Video available from http://www.sciencedaily.com/releases/2014/10/141001090246.htm.
- Long-lasting insulin more effective than intermediate acting – NewsMaxHealth- Published Online. (October 3, 2014). Video available from http://www.newsmaxhealth.com/Health-News/insulin-Type-1-diabetes-long-lasting-intermediate-lasting/2014/10/03/id/598476/.
- Long-acting insulin ‘probably superior’ to intermediate-acting insulin - Pharmaceutical Journal. (October 3, 2014). Video available from http://www.pharmaceutical-journal.com/news-and-analysis/research-briefing/long-acting-insulin-probably-superior-to-intermediate-acting-insulin/20066717.article.
- Study compares insulin regimens for type 1 diabetes – WebMD- Published Online. (October 3, 2014). Video available from http://www.webmd.com/diabetes/news/20141003/study-compares-insulin-regimens-for-type-1-diabetes.
- Long-acting insulin safer, more effective – DailyTelegraph- Published Online. (October 2, 2014). Video available from http://www.dailytelegraph.com.au/news/breaking-news/long-acting-insulin-safer-more-effective/story-fni0xqlk-1227077408318.
- Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis. (October 1, 2014). Video available from http://www.bmj.com/content/349/bmj.g5459.long.