Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis
Tricco AC, Chit A, Soobiah C, Hallett D, Meier G, Chen MH, Tashkandi M, Bauch CT, Loeb M. Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis. BMC Med. 2013 Jun 25;11:153. doi: 10.1186/1741-7015-11-153.
[sidebar] Funder: GlaxoSmithKline, Canada
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[ssba-buttons] [/sidebar] [sidebar-content]- Our results can help public health officials anticipate the possible infection and complications from influenza during mismatched years
- Estimates of protection for mismatched influenza seasons can be used by patients who are contemplating immunization
- Results were used to inform a cost-effectiveness model on vaccination for influenza
- Featured in >50 mass media articles
- The live-attenuated influenza vaccine (LAIV) and trivalent inactivated vaccine (TIV) have been shown to offer benefit(s) during matched seasons, as well as mismatched seasons
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Date : 25 Aug 2020