Reporting Bias

    Selective Reporting Bias in Randomised Controlled Trials from Two Network Meta-Analyses: Comparison of Clinical Trial Registrations and their Respective Publications

    Wong EK, Lachance CC, Page MJ, Watt J, Veroniki A, Straus SE, Tricco AC. Selective reporting bias in randomised controlled trials from two network meta-analyses: comparison of clinical trial registrations and their respective publications. BMJ Open. 2019;9(9):e031138. doi: 10.1136/bmjopen-2019-031138.

     

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    Impact:

    • This study aims to determine if there is a difference in the frequency of overall serious adverse events (SAEs) reported in clinical trial registrations and their respective primary publications
    • This study was conducted for systematic review authors who incorporate safety data into meta-analyses and network meta-analyses

    Protocol:

    Funding:

    Dr. Sharon E. Straus is funded by a Tier 1 Canada Research Chair (CRC) in Knowledge Translation. Dr. Andrea C. Tricco is funded by a Tier 2 Canada Research Chair (CRC) in Knowledge Synthesis and Ontario Ministry of Research, Innovation, and Science Early Researcher Award (2015 to 2020).

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    Date : 27 Feb 2018