Long-acting Muscarinic Antagonists for Chronic Obstructive Pulmonary Disease

    Comparative Safety and effectiveness of long-acting muscarinic antagonists for chronic obstructive pulmonary disease (COPD): a rapid review and network meta-analysis

    Tricco AC, Strifler L, Yazdi F, Khan P, Ng C, Antony J, Mrklas K, Scott A, D’Souza J, Cardoso R. Comparative safety and effectiveness of long-acting muscarinic antagonists for chronic obstructive pulmonary disease (COPD): a rapid review and network meta-analysis. Technical Report 2014.

     

    [sidebar] Commissioned and Funded by: Ontario Drug Policy Research Network (ODPRN) and Ontario Ministry of Health and Long-Term Care (OMHLTC)

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    • Our results can be used by patients and physicians to tailor administration of these agents
    • Commissioned by the Ontario Drug Policy Research Network to inform the listing of these agents by the Ontario Public Drug Program
    • The results of a network meta-analysis (NMA) restricted to patients with moderate chronic obstructive pulmonary disease (COPD) found that tiotropium+formoterol had the highest probability of reducing the risk of exacerbations

     

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    Date : 03 Sep 2020