PROSPERO

    A third of systematic reviews changed or did not specify the primary outcome: a PROSPERO register study

    Tricco AC, Cogo E, Page MJ, Polisena J, Booth A, Dwan K, MacDonald H, Clifford TJ, Stewart LA, Straus SE, Moher D. A third of systematic reviews changed or did not specify the primary outcome: a PROSPERO register study. J Clin Epidemiol. 2016 Nov;79:46-54. doi: 10.1016/j.jclinepi.2016.03.025.

     

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    Funder: No funding was received for this study

     

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    • This study aims to promote transparency and reduce discrepancies in review conduct by encouraging:
      • Review authors to register all non-Cochrane reviews in PROSPERO
      • Review authors to carefully consider the selection of primary outcomes
      • Peer reviewers to check PROSPERO to see if there are any discrepancies between the record and review publication
      • Journals to focus acceptance on registered systematic reviews
    • Approximately one-third of systematic reviews that are registered in PROSPERO have discrepancies in primary outcomes between their record and review publication

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    Date : 10 Dec 2019